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Details of Grant 

EPSRC Reference: GR/R92592/01
Title: Virtual tissue engineering of gravid uterus
Principal Investigator: Holden, Professor A
Other Investigators:
Smye, Professor S Simpson, Dr N Clayton, Professor RH
Researcher Co-Investigators:
Project Partners:
Department: School of Biomedical Sciences
Organisation: University of Leeds
Scheme: Standard Research (Pre-FEC)
Starts: 01 April 2003 Ends: 31 August 2006 Value (£): 117,544
EPSRC Research Topic Classifications:
Tissue Engineering
EPSRC Industrial Sector Classifications:
Related Grants:
Panel History:  
Summary on Grant Application Form
Computational models and methods that have been developed for understanding synchronisation and propagation phenomena in heart muscle will be adapted and applied to the gravid uterus. Models of uterine smooth muscle and uterine anatomy will be constructed , used to explore the quantitative effects of changes in excitability and cell-to-cell coupling, and validated against published results and clinical data that are being recorded at Leeds. We anticipate identifying measures of electrical activity that will identify and predict the onset of labour, and quantify some dysfunctions
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Further Information:  
Organisation Website: http://www.leeds.ac.uk