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Details of Grant 

EPSRC Reference: EP/R007500/1
Title: On Demand microPAD Mass Spectrometry
Principal Investigator: Maher, Dr S
Other Investigators:
Lightman, Professor SL
Researcher Co-Investigators:
Project Partners:
Q Technologies Ltd Sensor City
Department: Electrical Engineering and Electronics
Organisation: University of Liverpool
Scheme: First Grant - Revised 2009
Starts: 31 July 2017 Ends: 30 September 2018 Value (£): 100,948
EPSRC Research Topic Classifications:
Analytical Science
EPSRC Industrial Sector Classifications:
Healthcare
Related Grants:
Panel History:
Panel DatePanel NameOutcome
31 May 2017 HT Investigator-led Panel Meeting - May 2017 Announced
Summary on Grant Application Form
In order to realise the full potential of Mass Spectrometry (MS), conventional approaches require extensive, expensive and careful sampling and associated preparation. For clinical samples, quantitative analysis usually requires extraction followed by 'hyphenated' separation (e.g., chromatography) and finally mass spectrometric detection. In the pursuit of highly sensitive, specific and precise quantitation, such analytical methods involve extensive sample preparation, resulting in increased cost and time of analysis. This proposal seeks a radical solution to how we perform such analyses. The outcomes of this work will lead to a new type of paper-based sensor for in-situ sample collection, separation, extraction and ionisation all achieved from a single paper substrate for coupling with MS. To that end, this new approach will be demonstrated for the analysis of steroid hormones of clinical significance.
Key Findings
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Potential use in non-academic contexts
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Impacts
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Summary
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Organisation Website: http://www.liv.ac.uk