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Details of Grant 

EPSRC Reference: EP/L012952/1
Title: Clinical Infrared and Raman Spectroscopy Network (CLIRSPEC)
Principal Investigator: Gardner, Professor P
Other Investigators:
Baker, Dr MJ
Researcher Co-Investigators:
Project Partners:
Agilent Technologies Ltd Bruker Christie NHS Foundation Trust
Cobalt Light Systems Ltd Diamond Light Source Dublin Institute of Technology
Gloucestershire Hospitals NHS Fdn Trust Horiba UK Ltd Imperial College London
Keele University Lancashire Teaching Hospitals NHS Trust Lancaster University
Monash University Perkin Elmer Renishaw
Robert Koch Institute Royal Devon and Exeter Hospital UCL
UCL Hospitals NHS Trust University of Exeter University of Liverpool
University of Manchester, The University of Reims Champagne-Ardenne VS Consulting
Department: Chem Eng and Analytical Science
Organisation: University of Manchester, The
Scheme: Network
Starts: 01 February 2014 Ends: 30 April 2017 Value (£): 188,407
EPSRC Research Topic Classifications:
Analytical Science Biomedical sciences
EPSRC Industrial Sector Classifications:
Healthcare
Related Grants:
Panel History:
Panel DatePanel NameOutcome
17 Oct 2013 EPSRC Physical Sciences Chemistry - October 2013 Announced
Summary on Grant Application Form
A major part of the diagnosis of any disease but particularly various forms of cancer, is obtained though a biopsy. This involves removing a small sample of tissue, or a few cells, from the patient. These samples, either tissue or cells are then examined by a pathologist looking down an optical microscope. In most cases the sample is stained with a combination of dyes to help gain some contrast. In most cases, based upon visual inspection of the sample a diagnosis is made. This process if far from ideal since it relies on the expertise of the clinician concerned as is subject to intra in inter observer error. Recently a number of proof of concept studies have shown that molecular spectroscopic techniques such as infrared and Raman are capable of distinguishing diseased from non diseased cells and tissue based upon the inherent chemistry contained within the cells. The UK is at the forefront of these developments but there are many hurdles that need to be overcome if this technology is to move from the proof of concept stage through the translational stage and into the clinical setting. It is the belief of the academic community that we are much more likely to overcome these hurdles if we pool our resources, bring in both industrial and clinical partners and work on these generic problems together. This application is for funding to support such a network of partners for the next three years.

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Organisation Website: http://www.man.ac.uk