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EPSRC Support by Research Area in Chemical Biology and Biological Chemistry

Research areas are used to describe EPSRC's portfolio of excellent long term research and high quality postgraduate training.

Grants are classified using one or more research areas. All the grants listed below have some relevance to this research area. The value of the investment is the total awarded by EPSRC and does not reflect the proportion assigned to this research area.

We always try to ensure that grants on the web contains the most recent information but it is possible that some might be slightly out of date.

Grant TitlePrincipal
Investigator
OrganisationDepartmentTotal Grant
Value (£)
A New Front in the War on Superbugs: Synthetic and Biological Studies on the Potent Antibiotic AnthracimycinClarke, Dr PAUniversity of YorkChemistry 599,011
A novel tumour-responsive formulation for delivering sonodynamic treatment of prostate cancerNomikou, Dr NUCLNanotechnology 101,014
Accurate free energy calculations for biomolecular catalysis of electron transferRosta, Dr EKings College LondonChemistry 100,972
An Investigation of Multicomponent Azole Chemistry within a Generational System for the Expression the Canonical Genetic StructuresPowner, Dr MWUCLChemistry 970,490
Aston Multidisciplinary Research for Antimicrobial Resistance: The AMR4AMR projectPitt, Professor ARAston UniversitySch of Life and Health Sciences 729,459
Augmenting Oxford's Centre for Advanced Electron Spin Resonance with a Bruker Elexsys E580 X/Q-band pulsed ESR spectrometerArdavan, Professor AUniversity of OxfordOxford Physics 90,301
Autonomous Discovery of Functional Small MoleculesNelson, Professor ASUniversity of LeedsSch of Chemistry 1,245,808
Bridging the Gaps: Systems-level approaches to antimicrobial resistanceKing, Professor JUniversity of NottinghamSch of Mathematical Sciences 491,232
BristolBridge: Bridging the Gaps between the Engineering and Physical Sciences and Antimicrobial ResistanceMulholland, Professor AJUniversity of BristolChemistry 592,169
Building the Queen's University of Belfast AMR Network (QUBAN)Bell, Professor SEJQueen's University of BelfastSch of Chemistry and Chemical Eng 395,371
Catalysis in motion: accessing how fast motions facilitate catalysis through pump-probe and fast time resolved spectroscopies.Scrutton, Professor NSUniversity of Manchester, TheChemistry 1,060,085
Cloud-based methods to predict the druggability of protein-protein interactions: applications to cancer and antimicrobial resistance.Laughton, Dr CAUniversity of NottinghamSch of Pharmacy 293,994
Cobalt- and Nickel-based Polymetallocenes: Functional Metallopolymers from Earth-Abundant MetalsO'Hare, Professor DUniversity of OxfordOxford Chemistry 19,612
Cobalt- and Nickel-based Polymetallocenes: Functional Metallopolymers from Earth-Abundant MetalsManners, Professor IUniversity of BristolChemistry 263,683
Cross-scale prediction of Antimicrobial Resistance: from molecules to populations.Keeling, Professor MUniversity of WarwickMathematics 501,448
Delivering antibodies (molecular weight = 150 kDa) to the brainUchegbu, Professor IUCLSchool of Pharmacy 741,548
Designer Chemistry to Probe Supramolecular Assembly Mechanism and FunctionWilson, Professor AJUniversity of LeedsSch of Chemistry 458,233
Designer hybrid chemo-enzymatic catalysts for cofactor recyclingPordea, Dr AUniversity of NottinghamFaculty of Engineering 99,728
Dinuclear ruthenium light-switches as multi-output sub-cellular imaging probes within live cells and tissuesThomas, Professor JAUniversity of SheffieldChemistry 711,979
Direct observation and characterisation of physical autocatalysis by interferometric scattering microscopyFletcher, Professor SPUniversity of OxfordOxford Chemistry 580,471
Diversity-Oriented Synthesis of Stapled PeptidesSpring, Professor DUniversity of CambridgeChemistry 1,205,345
Efficient modelling and validation of cryptic protein binding sites for drug discoveryMichel, Dr JUniversity of EdinburghSch of Chemistry 198,251
Efficient modelling and validation of cryptic protein binding sites for drug discoveryGervasio, Professor FUCLChemistry 272,316
Enabling ultra-high resolution hydrogen/deuterium exchange for challenging biomedical systemsZhuravleva, Dr AUniversity of LeedsAstbury Centre 100,792
Engineering Multi-functional Nanomaterials to Treat Metastatic CancerAl-Jamal, Dr WUniversity of East AngliaPharmacy 99,870
Enzymatic tools for biotechnology and medicineNeely, Dr RKUniversity of BirminghamSchool of Chemistry 1,000,807
EPSRC and MRC Centre for Doctoral Training in Systems Approaches to Biomedical ScienceDeane, Professor CUniversity of OxfordMathematical, Physical&Life Sciences Div 3,552,382
EPSRC Centre for Doctoral Training in Physical Sciences for Health (Sci-Phy-4-Health)Hannon, Professor MJUniversity of BirminghamSchool of Chemistry 3,509,723
EPSRC Centre for Doctoral Training in Physical Sciences Innovation in Chemical Biology for Bioindustry and HealthcareCes, Dr OImperial College LondonDept of Chemistry 4,617,554
EPSRC Centre for Doctoral Training in Synthesis for Biology and MedicineDixon, Professor DJUniversity of OxfordOxford Chemistry 4,811,030
EPSRC Flagship Software - BioSimSpace: A shared space for the community development of biomolecular simulation workflowsMichel, Dr JUniversity of EdinburghSch of Chemistry 523,963
EPSRC-Royal Society Fellowship Engagement (2013): Site-specific fluorination of peptides and proteinsBernardes, Dr GJLUniversity of CambridgeChemistry 278,081
Establishing a Design Blueprint for Nanomedicines for Oral Drug DeliveryVllasaliu, Dr DUniversity of LincolnSchool of Pharmacy 101,218
Establishing an Approach for the Selection and Design of Secondary Structure Mimetics to Antagonise Protein-protein Interactions.Mason, Dr JMUniversity of BathBiology and Biochemistry 26,426
EuroTracker Dyes: Synthesis and Application in Functional Cell ImagingParker, Professor DDurham, University ofChemistry 357,832
Evaluation of next generation nanocomposite polymer coated stents incorporating stem cell capture technology for enhanced in situ endothelialisation.Cousins, Dr BUCLSurgery 732,452
Exploring Delocalised Energy Transport in Bacterial Reaction CentresOliver, Dr TUniversity of BristolChemistry 100,963
Fluorovinyl thioethers as stereoelectronic mimetics of acyl co-enzyme-A enol/atesO'Hagan, Professor DUniversity of St AndrewsChemistry 400,859
Foresight Fellowship in Manufacturing: "High-throughput functionalization of biomaterials for personalized healthcare"Webb, Dr SJUniversity of Manchester, TheChemistry 124,188
From nature to nano: structure, dynamics and reactivity of DNA three-way junctionsMagennis, Dr SWUniversity of GlasgowSchool of Chemistry 316,236
Gram-Scale Synthesis of Brevianamide Alkaloids.Lawrence, Dr A LUniversity of EdinburghSch of Chemistry 99,123
High Resolution Solid State Nitrogen-14 NMRCarravetta, Dr MUniversity of SouthamptonSchool of Chemistry 475,926
How does respiratory complex I pumps protons? Finding the missing link using EPR spectroscopy.Roessler, Dr M MQueen Mary, University of LondonSch of Biological and Chemical Sciences 100,373
Identifying Energy Dispersal Pathways in Bare and Hydrated Nuclear Bases: A New Dimension in Nanosecond Electronic SpectroscopyWright, Professor TUniversity of NottinghamSch of Chemistry 717,205
Industrial Doctorate Centre: Systems Approaches to Biomedical ScienceDeane, Professor CUniversity of OxfordMathematical & Physical Sciences Div 6,627,547
Integrated computational and synthetic tools to drive the discovery of orthosteric protein-protein interaction inhibitorsWilson, Professor AJUniversity of LeedsSch of Chemistry 2,751,527
Integrated workflows for glycan analysis: tagging strategies to facilitate structural and functional characterisation of carbohydratesAllman, Dr SOpen UniversityFaculty of Sci, Tech, Eng & Maths (STEM) 100,802
Lanthanide complexes as chiral probes and labelsParker, Professor DDurham, University ofChemistry 582,868
'Last step' enzymatic [18F]-labelling of peptides for Positron Emission Tomography (PET)O'Hagan, Professor DUniversity of St AndrewsChemistry 341,488
'Last step' enzymatic [18F]-labelling of peptides for Positron Emission Tomography (PET)Zanda, Professor MUniversity of AberdeenSchool of Medical Sciences 77,673
Live cell super-resolution microscopy assessment of targeted unimolecular nanomachinesPal, Dr RDurham, University ofChemistry 1,613
LSI Doctoral Training Centres - Doctoral Training Centre in Cell & Proteomic TechnologiesCooper, Professor JUniversity of GlasgowInstitute of Biomedical & Life Sciences 4,820,424
LSI Doctoral Training Centres - Molecular organisation and assembly in cells (MOAC) doctoral training centreRodger, Professor AUniversity of WarwickChemistry 5,496,421
LSI Doctoral Training Centres - The doctoral training centre in chemical biologyTempler, Professor RImperial College LondonDept of Chemistry 4,752,733
LSI DTCs 2007: Physical sciences of imaging in the biomedical sciences (PSIBS)Hannon, Professor MJUniversity of BirminghamSchool of Chemistry 7,181,445
Metal-free couplings for molecules, materials and bioactive targetsProcter, Professor DJUniversity of Manchester, TheChemistry 1,146,757
Mimetic sugar nucleotides to probe a strategic bacterial dehydrogenase enzymeMiller, Dr GKeele UniversityFaculty of Natural Sciences 245,957
Minimal DNA Nanopores for Electrical Sensing of ProteinsHoworka, Dr SUCLChemistry 405,368
Molecular Dynamics and EPR spectroscopy on lipid bilayers: new approaches to study biological membranesOganesyan, Dr VUniversity of East AngliaChemistry 464,262
Molecular Dynamics and EPR spectroscopy on lipid bilayers: new approaches to study biological membranesWilson, Professor MRDurham, University ofChemistry 54,337
Nanoanalysis for Advanced Materials and HealthcareMartin, Professor RWUniversity of StrathclydePhysics 13,061
Nanoscale metallomics and mineralization: advanced spectro-microscopy determination of the role of iron and calcium in Alzheimer's diseaseCollingwood, Dr JFUniversity of WarwickSch of Engineering 418,210
Nanoscale metallomics and mineralization: advanced spectro-microscopy determination of the role of iron and calcium in Alzheimer's diseaseTelling, Dr NDKeele UniversityInst for Science and Tech in Medicine 337,549
Nicotinic Ligand Development to Target Smoking Cessation and Gain a Molecular Level Understanding of Partial AgonismGallagher, Professor TUniversity of BristolChemistry 724,553
Novel ionic-based tools for glycoscienceGalan, Dr MUniversity of BristolChemistry 920,060
Opening the door to novel antibody fragment-based therapeutics and diagnostics via a "dual click" strategyCaddick, Professor SUCLChemistry 564,009
Orthogonal Modules Engineered for Synthetic Protein- and Microbial-NetworksHowarth, Professor MRUniversity of OxfordBiochemistry 372,234
Palladium-activated prodrug therapy: a novel focal therapy for localised cancers of unmet needUnciti-Broceta, Dr AUniversity of EdinburghEdinburgh Cancer Research Centre 1,074,212
PET Markers of Oligomeric Misfolded Proteins in Neurodegenerative DisordersAigbirhio, Professor FIUniversity of CambridgeWolfson Brain Imaging Centre 1,041,821
Predicting drug-target binding kinetics through multiscale simulationsMulholland, Professor AJUniversity of BristolChemistry 225,397
Predicting drug-target binding kinetics through multi-scale simulationsGervasio, Professor FUCLChemistry 245,251
Profiling the „Methylome? Targets of the Histone Lysine Methyltransferases: DOT1LFuchter, Dr MatthewImperial College LondonDept of Chemistry 141,506
Radiotherapy activated materials for enhanced cancer treatmentsAlexander, Professor CUniversity of NottinghamSch of Pharmacy 539,154
Restricted Diversity; Constrained Diversity-Oriented SynthesisSpring, Professor DUniversity of CambridgeChemistry 1,541,796
Sensors for clean water: a participatory approach for technology innovationJohnson, Dr SDUniversity of YorkElectronics 1,182,012
SI2-CHE: CCP-SAS - Collaborative Computational Project for advanced analyses of structural data in chemical biology and soft condensed matterPerkins, Professor SUCLStructural Molecular Biology 556,960
Siderophores as anchors in artificial metalloenzymesDuhme-Klair, Professor AUniversity of YorkChemistry 627,905
Software for experimentally driven macromolecular modellingDegiacomi, Dr MDurham, University ofChemistry 687,453
Structural Dynamics in LOV Domain Photosensor ProteinsMeech, Professor SUniversity of East AngliaChemistry 352,953
Structural studies of atomic interactions in membranes: bridging the gap between physics and membrane biologyMcLain, Dr SUniversity of OxfordBiochemistry 1,345,845
Substrate Peptidomimetic Inhibitors (SPIs) of the COP9 signalosomeKessler, Dr BMUniversity of OxfordTarget Discovery Institute 116,018
Substrate Peptidomimetic Inhibitors (SPIs) of the COP9 signalosomeEchalier, Dr AUniversity of LeicesterMolecular and Cell Biology 347,943
Synthesis and Biology of ProstanoidsAggarwal, Professor VKUniversity of BristolChemistry 1,061,277
Synthesis and characterisation of DNA adducts derived from the bracken toxin ptaquiloside.Williams, Dr DUniversity of SheffieldChemistry 354,312
Synthesis of the RNA polymerase inhibitor tagetitoxinPorter, Dr MJUCLChemistry 389,768
Tandem organocatalysis for the bi-functional modification of proteinsFascione, Dr M AUniversity of YorkChemistry 100,609
TARGeTED: Tackling Antimicrobial Resistance through Goal-orientated Thinking in the EPS DisciplinesSmith, Professor MCMUniversity of YorkResearch and Enterprise Office 402,902
The quantitative analysis of signalling dynamics in breast cancer : an interdisciplinary approachBaum, Dr BuzzUCLMRC Laboratory of Molecular Cell Biology 163,944
The Realisation of Fragment-Oriented SynthesisMarsden, Professor SPUniversity of LeedsSch of Chemistry 574,490
The UK High-End Computing Consortium for Biomolecular SimulationMulholland, Professor AJUniversity of BristolChemistry 288,481
Time resolved in cellulo studies on luminescent metal complex-based cell probesThomas, Professor JAUniversity of SheffieldChemistry 3,953
Transmission Electron Microscopy: Essential Support for Materials SynthesisAbell, Professor CUniversity of CambridgeChemistry 1,932,306
Ultrafast Dynamics at Protein InterfacesMeech, Professor SUniversity of East AngliaChemistry 296,001
Underpinning Equipment for Magnetic Resonance ResearchSpearing, Professor SMUniversity of SouthamptonSchool of Chemistry 1,999,099
Wellcome EPSRC Centre for Medical EngineeringRazavi, Professor RSKings College LondonImaging & Biomedical Engineering 5,934,858

Total Number of Grants: 95
Total Value of Grants: £95,698,647

The grant value may include the cost of access to facilities (these funds are not awarded to the grant holding organisation).